# Editorial: High-throughput sequencing-based investigation of chronic disease markers and mechanisms, volume II

**Authors:** Hua Li, Guoshuai Cai, Wen-Lian Chen, Xiaodong Zhao, Yuriy L. Orlov

PMC · DOI: 10.3389/fgene.2025.1627976 · Frontiers in Genetics · 2025-05-29

## Full-text entities

- **Genes:** SYNGAP1 (synaptic Ras GTPase activating protein 1) [NCBI Gene 8831] {aka MRD5, RASA5, SYNGAP}, IMPA1 (inositol monophosphatase 1) [NCBI Gene 3612] {aka IMP, IMPA, MRT59}, LZTFL1 (leucine zipper transcription factor like 1) [NCBI Gene 54585] {aka BBS17}, PDE1A (phosphodiesterase 1A) [NCBI Gene 5136] {aka CAM-PDE 1A, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A}, ILF2 (interleukin enhancer binding factor 2) [NCBI Gene 3608] {aka NF45, PRO3063}, SLC6A20 (solute carrier family 6 member 20) [NCBI Gene 54716] {aka IMINO, SIT1, XT3, Xtrp3}, SEMA3D (semaphorin 3D) [NCBI Gene 223117] {aka Sema-Z2, coll-2}, NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}
- **Diseases:** neuromuscular degeneration (MESH:D009468), colorectal cancer (MESH:D015179), type 2 diabetes mellitus (MESH:D003924), COVID-19 (MESH:D000086382), Duchenne muscular dystrophy (MESH:D020388), obese (MESH:D009765), Gastrointestinal and metabolic diseases (MESH:D005767), HL (MESH:C538324), metabolic syndromes (MESH:D024821), Crohn's disease (MESH:D003424), cancer (MESH:D009369), Infection (MESH:D007239), intellectual disability (MESH:D008607), inflammatory bowel disease (MESH:D015212), Disease (MESH:D004194)
- **Chemicals:** calcium (MESH:D002118), YG-22 (-), iron-oxide (MESH:C000499)
- **Species:** Homo sapiens (human, species) [taxon 9606], Grass carp reovirus (no rank) [taxon 128987], Danio rerio (leopard danio, species) [taxon 7955], Mus musculus (house mouse, species) [taxon 10090], Ctenopharyngodon idella (grass carp, species) [taxon 7959]
- **Mutations:** rs17713054, c.664-2A>G

## Full text

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12159017/full.md

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Source: https://tomesphere.com/paper/PMC12159017