# Editorial: Next generation micro-physiological systems for pragmatic use in regular industrial workflow

**Authors:** Ali Kermanizadeh, David M. Brown, Wolfgang Moritz

PMC · DOI: 10.3389/fcell.2025.1607979 · Frontiers in Cell and Developmental Biology · 2025-05-29

## Full-text entities

- **Genes:** FAP (fibroblast activation protein alpha) [NCBI Gene 2191] {aka DPPIV, FAPA, FAPalpha, SIMP}, PNPLA3 (patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase) [NCBI Gene 80339] {aka ADPN, C22orf20, iPLA(2)epsilon}
- **Diseases:** Tumour (MESH:D009369), liver acinus (MESH:D017093), T (MESH:D001260), metabolic syndrome (MESH:D024821), hepatocyte hypertrophy (MESH:D006984), liver damage (MESH:D056486), chronic liver disease (MESH:D008107), toxicity (MESH:D064420), breast cancer (MESH:D001943), MPS (MESH:C536681)
- **Chemicals:** resmetirom (MESH:C588408), Compound G (-), phenobarbital (MESH:D010634)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** LX-2 — Homo sapiens (Human), Transformed cell line (CVCL_5792), THP-1 — Homo sapiens (Human), Childhood acute monocytic leukemia, Cancer cell line (CVCL_0006), Caco-2 — Homo sapiens (Human), Colon adenocarcinoma, Cancer cell line (CVCL_0025)

## Full text

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Source: https://tomesphere.com/paper/PMC12158916