# Chinese expert consensus on screening and clinical application of monoclonal immunoglobulins (2025)

## TL;DR

This paper presents a Chinese expert consensus on screening and clinical use of monoclonal immunoglobulins to help detect related diseases early.

## Contribution

The paper provides a systematic consensus on M protein screening methods and their clinical applications in China.

## Key findings

- M protein screening helps in the early detection of M protein-related diseases.
- The consensus outlines existing screening methods and their clinical application ranges.
- Experts aim to improve early diagnosis rates through standardized guidelines.

## Abstract

单克隆免疫球蛋白（M蛋白）是克隆性B细胞或浆细胞分泌的同种免疫球蛋白或其片段（如轻链）。M蛋白相关疾病是一类以血和（或）尿中存在M蛋白为主要特征的疾病。M蛋白筛查有助于早期发现这类疾病。为提高M蛋白相关疾病的早期发现率，国内相关领域专家制定了本共识，系统介绍现有的M蛋白筛查方法及其临床应用范围，以指导临床实践。