# Impact of carotid artery revascularization on cognitive function: a study of symptomatic and asymptomatic cases

**Authors:** Sensen Wu, Yachan Ning, Hui Wang, Dikang Pan, Julong Guo, Cong Wang, Chunmei Wang, Yongquan Gu, Lianrui Guo

PMC · DOI: 10.3389/fneur.2025.1452495 · Frontiers in Neurology · 2025-05-29

## TL;DR

This study shows that carotid artery revascularization improves cognitive function, especially memory and attention, in both symptomatic and asymptomatic patients.

## Contribution

The study provides new evidence that cognitive improvements occur after carotid revascularization in both symptomatic and asymptomatic patients.

## Key findings

- Cognitive scores, including delayed recall, improved significantly after carotid revascularization.
- Attention improved in asymptomatic patients at 3 and 6 months post-surgery.
- Baseline clinical characteristics were similar between symptomatic and asymptomatic groups.

## Abstract

To investigate and compare changes in cognitive function following revascularization between patients with symptomatic and asymptomatic carotid stenosis.

From April 2019 to April 2022, patients carotid artery stenosis who were treated with carotid endarterectomy (CEA) or carotid artery stenting (CAS) were recruited for this study. The Montreal Cognitive Assessment (MoCA) instrument was used to evaluate cognitive function preoperatively and at 3, 6, and 12 months postoperatively. Patients were divided into two groups based on the neurological symptoms, repeated measures ANOVA was used for comparisons.

A total of 89 patients who met the criteria were enrolled and completed 1-year follow-up, divided into symptomatic group (32 patients) and asymptomatic group (57 patients). Baseline data showed no significant differences in clinical characteristics between the two groups. At 3, 6, and 12 months after carotid revascularization, the total MoCA and delayed recall scores for both groups showed significant increases compared to baseline levels. In patients with asymptomatic, attention also showed improvement at 3, 6 months compared to baseline (p < 0.05).

Carotid revascularization has a positive impact on cognitive function improvement, particularly in delayed recall and attention.

## Linked entities

- **Diseases:** carotid artery stenosis (MONDO:0001612)

## Full-text entities

- **Diseases:** carotid artery stenosis (MESH:D016893)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12158713/full.md

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Source: https://tomesphere.com/paper/PMC12158713