# Ruptured isolated spinal artery aneurysms: a rare manifestation of an arterial dissecting disease

**Authors:** T. P. Kee, T. Krings, J. Pace, S. K. Swaminathan, E. Orru'

PMC · DOI: 10.3389/fneur.2025.1567536 · Frontiers in Neurology · 2025-05-29

## TL;DR

This paper presents two cases of ruptured spinal artery aneurysms and reviews their rare condition and treatment approaches.

## Contribution

The paper contributes two clinical cases of ruptured ISAAs and a literature review on their management and pathophysiology.

## Key findings

- Two cases of ruptured posterior spinal artery aneurysms were successfully treated with surgery and embolization.
- Literature review highlights the unclear pathophysiology and non-standardized treatment of ISAAs.
- The paper emphasizes the rarity and challenges in managing isolated spinal artery aneurysms.

## Abstract

Isolated spinal artery aneurysms (ISAAs) are a rare cause of intracranial and spinal hemorrhages with unclear pathophysiology and natural history and non-standardized management strategies. We hereby present two cases of ruptured ISAAs of posterior spinal arteries treated with open surgery and embolization, respectively. Case presentations are followed by a comprehensive literature review on ISAA pathophysiology, natural history, and management strategies.

## Full-text entities

- **Diseases:** hemorrhages (MESH:D006470), intracranial (MESH:D001932), ISAAs (MESH:D002532), arterial dissecting disease (MESH:D000094665)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12158679/full.md

## References

86 references — full list in the complete paper: https://tomesphere.com/paper/PMC12158679/full.md

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Source: https://tomesphere.com/paper/PMC12158679