# Improvement of Gait Biomechanics after Endovascular Therapy for Patients with Intermittent Claudication Associated with Aortoiliac Occlusive Disease

**Authors:** Norinobu Ogasawara, Takaaki Kakihana, Daijirou Akamatsu, Yuta Tajima, Michihisa Umetsu, Takanori Ishida, Michiaki Unno, Hitoshi Goto, Takashi Kamei, Masahiro Kohzuki

PMC · DOI: 10.3400/avd.oa.25-00006 · Annals of Vascular Diseases · 2025-06-10

## TL;DR

Endovascular therapy improves gait in patients with aortoiliac artery disease and intermittent claudication.

## Contribution

This study is the first to show how gait biomechanics improve after endovascular therapy for aortoiliac occlusive disease.

## Key findings

- Gait parameters like step length and walking speed improved significantly one month after therapy.
- Hip flexor moment and pull-off power also showed significant improvement post-treatment.
- Six months postoperatively, gait parameters were no longer significantly different from healthy controls.

## Abstract

Objectives: Gait disturbances increase mortality rates in lower extremity artery disease. Changes in gait biomechanics after endovascular therapy for intermittent claudication associated with lower extremity artery disease remain unknown. This prospective study investigated the effect of endovascular therapy on gait biomechanics in intermittent claudication.

Methods: We recruited 10 patients (14 affected limbs) with intermittent claudication caused by isolated aortoiliac artery lesions who underwent endovascular therapy, and 10 healthy controls. Using 3-dimensional motion analysis, we measured biomechanical gait parameters preoperatively and over 6 months postoperatively, comparing them with those of healthy controls.

Results: One month after endovascular therapy, parameters improved significantly compared with preoperative values: step length (preoperative median 52.47 [interquartile range 47.11, 60.33]–postoperative 58.53 [54.63, 64.54] cm; P < 0.0037), walking speed (90.17 [73.98, 108.9]–103.49 [97.66, 117.94] cm/s; P = 0.0022), hip flexor moment (−0.75 [−1.04, −0.51] to −0.94 [−1.07, −0.74] Nm/kg; P = 0.04), and pull-off power generated by hip flexor muscles (H3, 0.68 [0.38, 1]–0.86 [0.72, 1.1] W/kg; P = 0.018). Preoperative joint power declined significantly compared to control parameters. However, 6 months postoperatively, no significant differences were observed.

Conclusions: Endovascular therapy for isolated aortoiliac artery lesions improved biomechanical gait parameters in patients with intermittent claudication.

## Full-text entities

- **Diseases:** lower extremity artery disease (MESH:D002539), aortoiliac artery lesions (MESH:D020765), Aortoiliac Occlusive Disease (MESH:D001157), Intermittent Claudication (MESH:D007383)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12158554/full.md

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Source: https://tomesphere.com/paper/PMC12158554