# Offloading Strategies Used for Plantar Diabetic Foot Ulcers and Their Outcomes in Real-Life Clinical Practice

## TL;DR

This study examines how different offloading devices affect healing in diabetic foot ulcers in real-world clinical settings.

## Contribution

The paper provides real-life evidence on the effectiveness of various offloading strategies for diabetic foot ulcers.

## Key findings

- 33% of patients achieved healing at 12 weeks, with no significant difference between offloading device types.
- Healing rates increased to 51.5% at 20 weeks and 77% at 1 year.
- Bandage shoes and felted foam were associated with more severe ulcers and multiple ulcers per foot.

## Abstract

Introduction: International guidelines describe offloading to facilitate healing as a cornerstone in the treatment of diabetes-related foot ulcers. In present-day clinics, various offloading devices are used. The aim of this paper is to describe the effectiveness in healing of different offloading devices used in real-life clinical practice in patients with diabetes-related foot ulcers. Methods: A retrospective cohort study of 235 patients with a plantar foot ulcer in one diabetic foot centre of expertise was used. Clinical outcomes were determined during a follow-up period of 12 months. Groups were defined according to the types of offloading. Univariate and multivariate analysis was performed to assess ulcer-related outcomes in different offloading devices. Results: Of the 235 patients, 3% were treated with a Total Contact Cast (TCC), 9% with an ankle-high removable device, 32% with a custom-made orthopaedic shoe, 16% with a bandage shoe, and 39% with felted foam. Patients who received a bandage shoe or felted foam had a higher UT classification (Stage D in 21% and 18%, respectively, p = 0.001) and more ulcers per foot (13% and 5%, respectively, p = 0.002). The overall healing rate at 12 weeks was 33% and was not significantly different between the offloading device groups (p = 0.255). Healing rates at 20 and 52 weeks were 51.5% and 77%. Conclusions: Removable ankle-high offloading devices, orthopaedic shoes, bandage shoes, and felted foam are the most frequently used for plantar diabetic foot ulcers in clinical practice. This seems to be the result of various physician- and patient-related factors such as logistical reasons, patient factors, and severity of complicated ulcers. Diabetic foot ulcer healing after 12 weeks, 20 weeks, and 1-year follow-up were consistent with previous observational studies.