# The Risk of Secondary Knee Procedures After Anterior Cruciate Ligament Reconstruction—A Nationwide Retrospective Cohort Study

**Authors:** Han-Kook Yoon, Chang-Min Lee, Hyun-Cheol Oh, Taemi Youk, Sang-Hoon Park

PMC · DOI: 10.3390/jcm14113823 · Journal of Clinical Medicine · 2025-05-29

## TL;DR

This study examines the risk of needing additional knee surgeries after ACL reconstruction, finding that many patients require secondary procedures like meniscectomy or knee replacement over time.

## Contribution

The study provides a nationwide analysis of secondary knee procedures following ACL reconstruction, identifying risk factors and procedure frequencies.

## Key findings

- 10.4% of patients underwent meniscectomy after ACL reconstruction.
- Graft type, gender, and age significantly influenced the risk of secondary procedures.
- Total knee arthroplasty occurred in 0.6% of patients following ACL surgery.

## Abstract

Objectives: Some following up patients have poor clinical outcomes when they experience anterior cruciate ligament reconstruction. The patient will undergo progression of knee joint osteoarthritis or several secondary knee procedures such as high tibial osteotomy, total knee arthroplasty, menisectomy, meniscus repair, or meniscus transplantation on their knees after anterior cruciate ligament reconstruction. This may be related to the remaining instability of the knee joint, changes in the knee joint biomechanics, and progression of osteoarthritis. This study aims to determine which secondary knee procedures are performed over time after anterior cruciate ligament reconstruction. Methods: The National Health Insurance Service-Health Screening database analyzed 146,122 patients who underwent ACL reconstruction surgery between 1 January 2002 and 31 December 2021. Secondary knee procedures were investigated by categorizing them into revisional reconstruction, high tibial osteotomy, total knee arthroplasty, menisectomy, meniscus repair, and meniscus transplantation, respectively. Multivariable Cox Proportional Hazard model analysis was used. The significant predictors for complications (p < 0.05) were as follows. Results: Among a total of 146,122 patients with anterior cruciate ligament reconstruction, 1073 (0.7%) patients underwent HTO, 908 (0.6%) patients underwent TKA, 15,218 (10.4%) patients underwent meniscectomy, 7169 (4.9%) patients underwent meniscus repair, and 938 (0.6%) patients underwent meniscus transplantation. The hazard ratio differed according to graft type, gender, and age group. Conclusions: Patients who undergo ACL reconstruction may experience poor clinical outcomes, such as progression of osteoarthritis and undergoing secondary knee procedures several years after ACL reconstruction. It is important for decision-making, ongoing monitoring, and follow-up care for patients undergoing ACL reconstruction.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** knee joint osteoarthritis (MESH:D020370), meniscus (MESH:D000070600), Anterior Cruciate Ligament (MESH:D000070598), osteoarthritis (MESH:D010003)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12156413/full.md

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Source: https://tomesphere.com/paper/PMC12156413