The Hungry Heart: Managing Cardiogenic Shock in Patients with Severe Anorexia Nervosa—A Case Report Series

TL;DR

This paper presents three cases of severe anorexia nervosa patients who developed cardiogenic shock and were successfully managed with intensive care and mechanical support.

Contribution

The paper highlights a multidisciplinary approach for managing cardiogenic shock in patients with severe anorexia nervosa.

Findings

Two patients were resuscitated after cardiac arrest and required mechanical circulatory support.

Careful electrolyte and nutritional management was crucial for recovery.

Early recognition and intervention improved survival in this high-risk group.

Abstract

Background: Cardiogenic shock is a life-threatening condition characterized by the failure of the heart to maintain adequate circulation, leading to multi-organ dysfunction. While it is most commonly associated with acute myocardial infarction or cardiomyopathies, cardiogenic shock can also arise in unusual settings, such as severe malnutrition in patients with anorexia nervosa, a psychiatric disorder characterized by extreme restriction of food intake. Methods: Here, we describe the management of three patients with anorexia nervosa and severe cardiogenic shock, who were treated in our cardiological intensive care unit between December 2022 and January 2025. Two patients were successfully resuscitated after experiencing cardiac arrest, and two required mechanical circulatory support, including Venoarterial Extracorporeal Membrane Oxygenation and microaxial flow pump. The patients presented with a range of complications including multi-organ failure and respiratory distress. Due to the fragile balance between intensive cardiac and nutritional management, as well as the comorbidity of chronic malnutrition, therapeutic decisions were made carefully, including cautious electrolyte management, targeted nutritional therapy, and the use of advanced circulatory support. Conclusions: The treatment approach and beneficious outcomes underline the necessity of a multidisciplinary strategy in managing these critically ill patients with complex, interwoven pathologies. Our experience suggests that early recognition of cardiogenic shock and timely intervention with mechanical circulatory support may significantly improve patient survival in this high-risk cohort. Careful management of nutritional therapy and supplementation of trace elements and vitamins is crucial.

Figures