# Cone Beam Computed Tomography in Oral Cancer: A Scoping Review

**Authors:** Muhammad Aiman Mohd Nizar, Syed Nabil

PMC · DOI: 10.3390/diagnostics15111378 · 2025-05-29

## TL;DR

This review summarizes how cone beam computed tomography is used in managing oral cancer, focusing on its roles in radiotherapy, bone assessment, surgery, and complication monitoring.

## Contribution

The study systematically categorizes current CBCT applications in oral cancer management, highlighting emerging uses and research gaps.

## Key findings

- CBCT is most commonly used for radiotherapy planning and monitoring in oral cancer.
- Bone invasion assessment is another major application of CBCT in this context.
- Emerging uses include intraoperative guidance and evaluating treatment complications.

## Abstract

Objectives: The present scoping review aims to explore and provide an overview of the current applications of cone beam computed tomography (CBCT) in the management of oral cancer. Methods: This study was conducted in accordance with the JBI Guidance for Scoping Reviews and reported following the PRISMA Extension for Scoping Reviews (PRISMA-ScR). A systematic search was performed across the following databases: PubMed, OVID, Scopus, Web of Science, and the Cochrane Library to answer the research question: “What are the current applications of CBCT in the perioperative management of patients with oral cancer?”. Results: A total of 52 studies met the inclusion criteria. Four major areas of CBCT application in oral cancer were identified: radiotherapy planning and monitoring (25 studies), assessment of bone invasion (16 studies), intraoperative surgical guidance (6 studies), and evaluation of treatment-related complications (5 studies). These findings highlight the diverse but focused use of CBCT across different stages of oral cancer management. Conclusions: CBCT is increasingly utilized in the perioperative management of oral cancer, with its application in radiotherapy planning and assessment being the most well-established. However, other uses, such as for surgical navigation and complication assessment, are still emerging, with promising evidence. Further research is needed to expand and validate these applications.

## Linked entities

- **Diseases:** oral cancer (MONDO:0023644)

## Full-text entities

- **Diseases:** Oral Cancer (MESH:D009062)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12155499/full.md

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Source: https://tomesphere.com/paper/PMC12155499