Changes of structural, magnetic and spectroscopic properties of microencapsulated iron sucrose nanoparticles in saline
Sabina Lewińska, Pavlo Aleshkevych, Roman Minikayev, Anna Bajorek, Mateusz Dulski, Krystian Prusik, Tomasz Wojciechowski, Anna Ślawska-Waniewska
TL;DR
This paper studies how microencapsulated iron sucrose nanoparticles change when dissolved in saline, focusing on their structural, magnetic, and spectroscopic properties.
Contribution
The study reveals how dissolution affects the magnetic and structural properties of microencapsulated iron sucrose nanoparticles.
Findings
Undissolved samples showed superparamagnetic behavior with a blocking temperature around 10 K.
Dissolution reduced the blocking temperature and altered the magnetic state of Fe3+ ions.
Nonintentional manganese contamination was detected in the completely dissolved sample via EPR.
Abstract
The structural and physical properties of microencapsulated iron sucrose and their changes upon dissolution in saline were tested. For the undissolved sample, calcium alginate microcapsules with irregular shapes were registered via scanning electron microscopy, inside which core–shell nanoparticles were identified by transmission electron microscopy micrographs. Magnetic studies (DC and AC) performed on the undissolved sample revealed the presence of a low temperature blocking process (<TB> ≈ 10 K), and confirmed its superparamagnetic state between 70– 250 K. X-ray photoelectron spectroscopy and Raman studies showed a varied composition of the undissolved sample in which organic compounds and SiO2 are the major phases, while the iron phase was recognized as iron oxyhydroxide (FeOOH) (most probably the α polymorph). The dissolution procedure had significant influence on structural and…
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Taxonomy
TopicsIron oxide chemistry and applications · Nanoparticle-Based Drug Delivery · Characterization and Applications of Magnetic Nanoparticles