# Large iliofemoral aneurysm harboring intramural fibrin-associated B-cell lymphoma

**Authors:** Christine L. Zickler, Jeffrey T. Bunning, Mikell Jarratt, Amber Johnson, Robert W. Zickler, Paul V. Kochupura

PMC · DOI: 10.1016/j.jvscit.2025.101810 · Journal of Vascular Surgery Cases, Innovations and Techniques · 2025-04-21

## TL;DR

This paper reports a rare case of a lymphoma found within a large aneurysm's clot, highlighting its unusual presentation.

## Contribution

The paper presents the second documented case of fibrin-associated B-cell lymphoma within an aneurysm's thrombus.

## Key findings

- FA-LBCL was identified within the mural thrombus of an iliofemoral aneurysm.
- The lymphoma was associated with Epstein-Barr virus.
- The case was discovered incidentally during histologic examination.

## Abstract

Fibrin-associated large B-cell lymphoma (FA-LBCL) is an extremely rare, non-mass forming lymphoproliferative disorder associated with Epstein-Barr virus (EBV). It is typically discovered incidentally on histologic examination of tissue removed for unrelated reasons. The following case report presents only the second reported case in the literature of FA-LBCL found proliferating within the mural thrombus of an aneurysm.

## Linked entities

- **Diseases:** lymphoproliferative disorder (MONDO:0016537)

## Full-text entities

- **Diseases:** thrombus (MESH:D013927), lymphoproliferative disorder (MESH:D008232), aneurysm (MESH:D000783), B-cell lymphoma (MESH:D016393)
- **Species:** human gammaherpesvirus 4 (Epstein Barr virus, no rank) [taxon 10376]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12151191/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12151191/full.md

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Source: https://tomesphere.com/paper/PMC12151191