# A Case–Control Study Examining the Differences in Vitamin D Levels Between Individuals With Rosacea and Healthy Individuals

## TL;DR

This study compared vitamin D levels in people with rosacea and healthy individuals but found no significant differences.

## Contribution

The study provides new evidence on the lack of association between vitamin D levels and rosacea.

## Key findings

- Vitamin D levels were slightly higher in rosacea patients but not significantly different from controls.
- No significant differences were found in vitamin D levels based on gender or disease severity.
- The study suggests vitamin D may not be a key factor in rosacea development.

## Abstract

Rosacea is an inflammatory and chronic skin condition that may be affected by many factors. The purpose of this study is to compare the level of vitamin D in two groups of cases (suffering from rosacea) and controls (healthy).

This case–control study was conducted in 2022 on 62 patients referred to Sedigheh Tahereh dermatology clinic, Isfahan, Iran. The criteria for entering the case group are to have rosacea based on the updated phenotype‐based diagnosis and classification system. Demographic variables such as age and gender as well as vitamin D levels were recorded for both case and control groups.

The mean of vitamin D level among patients with rosacea (29.9 ± 2.95) was higher than the control group (24.5 ± 2.14), but the difference was not statistically significant (p > 0.05). There was no significant difference in the mean of vitamin D level between rosacea patients and controls in gender or severity subgroups.

There is no significant difference in vitamin D levels between patients with rosacea and healthy individuals.