# Tuberculosis of the Lacrimal Gland: A Case Report

**Authors:** Anouar Ben Ameur El Youbi, Hajar El Youbi, Salma El Alaoui El Rhoul, Mohamed Afellah, Naouar Ouattassi, Mohammed Ridal, Najib Benmansour, Abdellatif Oudidi

PMC · DOI: 10.7759/cureus.83871 · Cureus · 2025-05-10

## TL;DR

This case report describes a rare instance of tuberculosis affecting the lacrimal gland, diagnosed through biopsy and successfully treated with anti-tuberculous therapy.

## Contribution

The paper presents a rare clinical case of primary mycobacterial infection of the lacrimal gland, emphasizing its diagnostic challenges and treatment.

## Key findings

- Tuberculosis of the lacrimal gland was confirmed via histopathological analysis of a biopsy.
- Anti-tuberculous therapy led to significant and sustained clinical improvement in the patient.
- The case highlights the importance of considering this rare condition in the differential diagnosis of lacrimal gland hypertrophy.

## Abstract

Tuberculosis of the lacrimal gland is a rare manifestation of extrapulmonary tuberculosis. It may occur in isolation or in association with pulmonary tuberculosis. The diagnosis is strongly supported by histopathological examination. Treatment relies on anti-tuberculous therapy. We report the case of a 53-year-old woman with no significant medical history who presented with chronic right-sided epiphora associated with the progressive appearance of a swelling in the region of the right lacrimal gland. A biopsy of the mass was performed, and histopathological analysis confirmed the diagnosis of tuberculous dacryoadenitis. The patient received anti-tuberculous therapy, which resulted in significant clinical improvement maintained over a one-year follow-up period. Primary mycobacterial infection of the lacrimal gland is extremely rare. Its clinical presentation is variable, making diagnosis challenging. Therefore, it should be considered in the differential diagnosis of any lacrimal gland hypertrophy, especially in endemic regions.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** gland (MESH:D000307), tuberculous dacryoadenitis (MESH:D003607), lacrimal gland hypertrophy (MESH:D006984), epiphora (MESH:D007766), Tuberculosis of the Lacrimal Gland (MESH:D014376), tuberculous (MESH:D014390), swelling (MESH:D004487), Primary mycobacterial infection (MESH:D009165), pulmonary tuberculosis (MESH:D014397)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12149662/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12149662/full.md

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Source: https://tomesphere.com/paper/PMC12149662