# Intubated patient of malignant central airway obstruction due to advanced esophageal cancer on ventilator support treated with radiotherapy: a case report

**Authors:** Shubham Dokania, Ajay K Choubey, Shashank Tiwari, Prasenjit Nath, Jhansi Pattanaik, Sambit S Nanda, Ashutosh Mukherji, Satyajit Pradhan

PMC · DOI: 10.3332/ecancer.2025.1895 · ecancermedicalscience · 2025-04-17

## TL;DR

A patient with advanced esophageal cancer causing airway blockage and needing a ventilator was successfully treated with radiotherapy, allowing for extubation.

## Contribution

This case report demonstrates the successful use of radiotherapy for extubation in a rare case of malignant central airway obstruction requiring ventilator support.

## Key findings

- Radiotherapy was used to treat malignant central airway obstruction in a patient on ventilator support.
- The treatment led to respiratory relief and successful extubation of the patient.
- This case highlights a potential treatment option when bronchoscopic interventions are not feasible.

## Abstract

Malignancies, associated directly or indirectly with airways, can cause a fatal condition, called malignant central airway obstruction (MCAO). Both endoluminal and extraluminal MCAO are conventionally treated using bronchoscopy-mediated therapies, but in patients unsuitable for bronchoscopic interventions, there are very limited options, especially if the patient needs ventilator support due to the obstruction. Few patients of carcinoma lung with MCAO needing ventilator support have been treated using radiotherapy (RT), with appreciable results. Though multiple risks are associated with shifting such patients out of the intensive care unit, these steps had to be carried out when RT was deemed the only possible solution. In this rare case of carcinoma esophagus with MCAO needing ventilator support and treated with RT, we have shown how RT can be used to increase the possibility of extubation of the patient. Hence, respiratory relief and extubation were aimed and achieved with RT in this case.

## Full-text entities

- **Diseases:** Malignancies (MESH:D009369), MCAO (MESH:D000402), carcinoma esophagus (MESH:D004938), carcinoma lung (MESH:D008175)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12149233/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12149233/full.md

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Source: https://tomesphere.com/paper/PMC12149233