# Penile Abscess Complicating Chronic Penile Calciphylaxis in a Heart Transplant Recipient and End-Stage Renal Disease Patient

**Authors:** Bharath P Bhushan, Sharath Rajagopalan, Vikash Kumar, David Shi, Eric Huang

PMC · DOI: 10.7759/cureus.85607 · 2025-06-09

## TL;DR

A rare case of penile abscess in a heart transplant patient with chronic penile calciphylaxis is presented, highlighting the challenges in diagnosis and treatment.

## Contribution

This case report adds to the limited literature on penile calciphylaxis and its rare complication of penile abscess in a heart transplant recipient.

## Key findings

- Penile calciphylaxis is rare and difficult to manage, especially in heart transplant recipients.
- Penile abscess is a rare but severe complication of chronic penile calciphylaxis.
- The case highlights the high mortality risk and management challenges associated with this condition.

## Abstract

Calciphylaxis, also known as calcific uremic arteriolopathy, is a rare but severe and life-threatening condition that is characterized by cutaneous arteriolar calcification and subsequent tissue necrosis. Calciphylaxis is more commonly seen in patients with end-stage renal disease (ESRD) and has a one-year mortality of greater than 50%. Penile calciphylaxis is extremely rare and carries a high mortality risk. Oftentimes, diagnosis and treatment are challenging. We present a case of a 71-year-old heart transplant recipient and end-stage renal disease patient with a history of chronic penile calciphylaxis who developed penile abscesses, highlighting the challenges of managing this complicated condition.

## Linked entities

- **Diseases:** calciphylaxis (MONDO:0017215), end-stage renal disease (MONDO:0004375)

## Full-text entities

- **Diseases:** Penile (MESH:D010409), necrosis (MESH:D009336), Calciphylaxis (MESH:D002115), ESRD (MESH:D007676), calcification (MESH:D002114), penile abscesses (MESH:D000038)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12147525/full.md

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Source: https://tomesphere.com/paper/PMC12147525