# A Nationwide Retrospective Analysis of Socioeconomic Factors Associated With Eosinophilic Colitis: A Population-Based Study

**Authors:** Bibek Karki, Samjhana Belbase, Michelle Bernshteyn, Ajit Brar, Hussain Murtaza, Nikky Maharjan, Navindra Dhakal, Subash Ghimire, Pujan Kandel, Calvin Ghimire, Philip McDonald, Matthew Lincoln, Michael Georgetson

PMC · DOI: 10.1016/j.gastha.2025.100663 · Gastro Hep Advances · 2025-03-22

## TL;DR

This study analyzed nationwide data to find that socioeconomic factors like race, gender, and insurance type are linked to hospitalizations for a rare colon inflammation called eosinophilic colitis.

## Contribution

The study reveals disparities in EC diagnosis and hospitalization based on race, gender, and insurance, highlighting healthcare inequities.

## Key findings

- Males were more likely to be hospitalized for EC than females.
- Caucasians made up the majority of EC cases, followed by African Americans and Hispanics.
- Private insurance was most common among EC patients, suggesting healthcare access disparities.

## Abstract

Eosinophilic colitis (EC) is a rare gastrointestinal inflammation of the colon characterized by eosinophilic infiltration into the colonic wall. The study aimed to assess the socioeconomic factors associated with EC.

A retrospective cohort study was conducted using the 2016–2020 National Inpatient Sample, including adult patients (≥18 years) admitted with EC.

Among 4353 EC cases identified, males are more likely to be hospitalized than females (51.8% vs 48.2%, P < .001). Caucasians consisted of 81.7% of total cases, followed by African Americans (8.1%), Hispanics (6.3%), and Asians (1.3%) (P < .001). 50.6% of EC cases had Private/Health Maintenance Organization insurance followed by Medicare (26.5%), Medicaid (15.7%), and 7.2% were uninsured (P < .001). Only 16.5% of patients had a Charlson Comorbidity Index ≥3.

Caucasians, males, and those with private insurance were more likely to be diagnosed with EC. The correlation between insurance coverage and hospitalizations shows health-care disparities and implies the need for equitable health-care delivery.

## Linked entities

- **Diseases:** eosinophilic colitis (MONDO:0018439)

## Full-text entities

- **Diseases:** EC (MESH:D003092), gastrointestinal inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12146004/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12146004/full.md

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Source: https://tomesphere.com/paper/PMC12146004