# The Interazygos Vein: A Case Report and Review of Preaortic Hemiazygos Anastomoses

**Authors:** Aarti N Sahai, Liliana M D'Alesio, Andrew L Dugaesescu, Jay M Bauman

PMC · DOI: 10.7759/cureus.83800 · Cureus · 2025-05-09

## TL;DR

A rare anatomical variation of the azygos vein system was discovered during a thoracic dissection and reviewed in existing literature.

## Contribution

This case report identifies and clarifies the clinical significance of a rare preaortic hemiazygos anastomosis known as the interazygos vein.

## Key findings

- The hemiazygos and accessory hemiazygos veins anastomosed into a vessel crossing anterior to the aorta before draining into the azygos vein.
- Literature review revealed that the term 'interazygos vein' includes various morphological variations.
- Awareness of this variation is crucial to prevent misdiagnosis and surgical complications.

## Abstract

During routine dissection of the thoracic cavity, a rare variation of the azygos system of veins was observed. The hemiazygos vein and the accessory hemiazygos vein generally course posterior to the aorta to form anastomoses with the azygos vein. However, in this case, the hemiazygos vein and the accessory hemiazygos vein anastomosed together into a vessel that crossed anterior to the thoracic aorta before draining into the azygos vein on the right side of the thoracic cavity. This variation is also known as an "interazygos vein."

While the venous system is recognized for its variability, a preaortic anastomosis is particularly rare. A literature review was conducted to investigate the morphology of previous reports of preaortic hemiazygos anastomoses and interazygos veins. It was determined that the term "interazygos vein" encompasses a range of morphological variations. Awareness of the interazygos vein is important clinically to avoid mediastinal misdiagnoses and surgical complications.

## Full-text entities

- **Diseases:** thoracic aortic aneurysms (MESH:D017545), hemorrhage (MESH:D006470), mediastinal tumors (MESH:D008479), venous thrombosis (MESH:D020246), respiratory failure (MESH:D012131)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12145863/full.md

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Source: https://tomesphere.com/paper/PMC12145863