# Signet Ring Cell Carcinoma of the Colon With Spermatic Cord Metastasis

**Authors:** Rin Morishita, Rina Fujiwara-Tani, Ruiko Ogata, Naokuni Tatsumoto, Hiroki Kuniyasu

PMC · DOI: 10.7759/cureus.83796 · Cureus · 2025-05-09

## TL;DR

A rare case of colon cancer spreading to the spermatic cord is reported, highlighting unusual metastasis patterns.

## Contribution

Documentation of a rare metastasis from colon cancer to the spermatic cord, expanding clinical awareness.

## Key findings

- A 53-year-old male with colon cancer developed metastasis to the spermatic cord.
- Histopathology confirmed the metastasis was signet ring cell carcinoma, matching the primary tumor.
- This case highlights an uncommon metastatic site for colorectal cancer.

## Abstract

We report a case of metastatic signet ring cell carcinoma (SRC) of the colon involving the right spermatic cord and testis following a right hemicolectomy. A 53-year-old male presented to our hospital in August 2020 with abdominal distension. Colonoscopy revealed a stenotic tumor in the transverse colon, and curative right hemicolectomy was performed. Histopathological examination confirmed colorectal cancer (CRC), classified as Stage IIIc. Postoperatively, capecitabine was administered for six months. In October 2021, the patient revisited our hospital with right scrotal swelling and pain. Although tumor markers were negative, CT revealed a tumor in the spermatic cord. Subsequently, orchiectomy and spermatic cord excision were performed. Histopathological findings confirmed SRC, consistent with the primary colon cancer diagnosed at age 53, and the lesion was considered a metastasis. This case represents an extremely rare occurrence of CRC of the colon, further complicated by metastasis to the spermatic cord, an uncommon metastatic site for CRC.

## Linked entities

- **Diseases:** signet ring cell carcinoma (MONDO:0005092), colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** SRC (MESH:D018279), pain (MESH:D010146), scrotal swelling (MESH:D014063), tumor (MESH:D009369), abdominal distension (MESH:D000007), CRC (MESH:D015179), Metastasis (MESH:D009362)
- **Chemicals:** capecitabine (MESH:D000069287)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12145856/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12145856/full.md

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Source: https://tomesphere.com/paper/PMC12145856