# From Infarction to Angiosarcoma: Unraveling the Mystery of Pericardial Hematoma

**Authors:** Chunna Jin, Yuhua Wang, Zhanglong Hu, Dandan Huang, Su Lin, Xiaohong Gu, Jun Jiang

PMC · DOI: 10.1016/j.jaccas.2025.103874 · JACC Case Reports · 2025-05-14

## TL;DR

This paper reports a rare case of angiosarcoma causing a pericardial hematoma following repeated heart attacks, highlighting the importance of imaging for diagnosis.

## Contribution

The novelty lies in presenting the first documented case of angiosarcoma onset via pericardial hematoma after multiple myocardial infarctions.

## Key findings

- Multimodality imaging aided in diagnosing angiosarcoma from pericardial hematoma.
- This case highlights a rare presentation of angiosarcoma following repeated heart attacks.
- Early diagnosis and preoperative planning were facilitated through combined imaging techniques.

## Abstract

Primary cardiac angiosarcomas are extremely rare, highly aggressive tumors characterized by rapid progression and high metastatic capability.

We present a case with unexplained pericardial hematoma after repeated right coronary infarction, combined with multimodality imaging and histopathologic examination, finally diagnosed as angiosarcoma.

There is no published case of angiosarcoma onset of pericardial hematoma after repeated myocardial infarction. Multimodality imaging contributes to early diagnosis and optimal preoperative planning.

## Linked entities

- **Diseases:** angiosarcoma (MONDO:0003022), myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** coronary infarction (MESH:C564258), tumors (MESH:D009369), Angiosarcoma (MESH:D006394), Pericardial Hematoma (MESH:D006406), Infarction (MESH:D007238), myocardial infarction (MESH:D009203)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12145000/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12145000/full.md

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Source: https://tomesphere.com/paper/PMC12145000