# Case Series on Varied Presentations of Amlodipine Toxicity

## TL;DR

This case series presents five instances of amlodipine toxicity with varied symptoms, including rare non-cardiogenic pulmonary edema.

## Contribution

The study highlights diverse and rare clinical presentations of amlodipine toxicity.

## Key findings

- Five cases of amlodipine toxicity showed varied clinical manifestations.
- Two cases presented with non-cardiogenic pulmonary edema, a rare symptom of amlodipine poisoning.

## Abstract

Calcium channel blockers (CCBs) are among the most widely prescribed drugs for cardiovascular illnesses. Angina pectoris, cardiac arrhythmias, hypertension, and other conditions are treated with calcium channel blockers (CCBs). Both immediate-release and extended-release versions of these drugs are available; the latter are often used in therapeutic settings.

While extended-release CCB overdoses can cause delayed start of dysrhythmias, shock, sudden cardiac collapse, and intestinal ischemia, immediate-release CCB overdoses are characterized by rapid progression to hypotension, bradydysrhythmia, and cardiac arrest. The present case series consists of five cases of amlodipine toxicity that were treated at Rajiv Gandhi General Government Hospital and had a range of clinical manifestations. The present case series also includes two cases of non-cardiogenic pulmonary edema, a rare presentation of amlodipine poisoning.