# Mammary Paget’s disease in a young woman: A rare occurrence

**Authors:** Chaimae Abourak, Aya Laridi, Ouafaa Chahboune, Siham Oukassem, Asmae Guennouni, Soukaina Bahha, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad

PMC · DOI: 10.1016/j.radcr.2025.04.062 · Radiology Case Reports · 2025-05-15

## TL;DR

A 47-year-old woman was diagnosed with rare Mammary Paget's disease linked to breast cancer, highlighting the need for thorough imaging and biopsy.

## Contribution

This case report adds to the limited literature on MPD in younger patients and emphasizes multimodal diagnostic approaches.

## Key findings

- MPD was confirmed through histopathology and associated with ductal carcinoma in situ.
- Multimodal imaging (mammography and MRI) was crucial for diagnosis.
- The case highlights the importance of considering MPD in atypical nipple presentations.

## Abstract

Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.

## Linked entities

- **Diseases:** Mammary Paget's disease (MONDO:0002648), ductal carcinoma in situ (MONDO:0005023), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** swelling (MESH:D004487), ductal carcinoma (MESH:D044584), MPD (MESH:D010144), inflammatory (MESH:D007249), breast malignancy (MESH:D001943), ductal carcinoma in situ (MESH:D002285), intraepithelial carcinoma (MESH:D002278), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12144428/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12144428/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12144428/full.md

---
Source: https://tomesphere.com/paper/PMC12144428