# Inflammatory Myofibroblastic Tumour of the Bladder in a Young Male: A Rare Case Report

**Authors:** Mohammad Hifzi Mohd Hashim, Suhaila Abdullah, Chin Yiun Lee, Syahril Anuar Salauddin, Hamid Hj Ghazali

PMC · DOI: 10.7759/cureus.83657 · Cureus · 2025-05-07

## TL;DR

A rare case of bladder tumor in a young male is reported, highlighting the importance of timely diagnosis and surgery for favorable outcomes.

## Contribution

This case report adds to the limited literature on inflammatory myofibroblastic tumor of the bladder in young males.

## Key findings

- The tumor was confirmed as IMT through histopathological and immunohistochemical analysis.
- The patient remained stable with no recurrence at three- and six-month follow-ups.
- Complete surgical excision is typically curative for bladder IMTs.

## Abstract

Inflammatory myofibroblastic tumour (IMT) of the urinary bladder is a rare mesenchymal neoplasm characterised by spindle-shaped myofibroblastic cells and an accompanying inflammatory infiltrate. Although its aetiology remains unclear, histopathological and immunohistochemical analyses are essential for diagnosis. We report the case of an 18-year-old male who presented with sudden-onset, painless gross haematuria. Initial evaluation revealed severe anaemia, necessitating blood transfusion. Renal ultrasound demonstrated a large echogenic lesion within the bladder. Cystoscopy revealed a large, polypoidal tumour on the right lateral bladder wall with active bleeding. The tumour was completely resected via transurethral resection of bladder tumour (TURBT). Histopathological examination confirmed IMT, with immunohistochemical staining positive for smooth muscle actin (SMA) and anaplastic lymphoma kinase (ALK), supporting the diagnosis. The patient remained stable postoperatively, with no recurrence at three- and six-month follow-up. Bladder IMTs are uncommon, particularly in young males, and typically present with non-specific urinary symptoms, most notably haematuria. Differentiation from other spindle cell neoplasms, including urothelial carcinoma and sarcomas, is crucial for appropriate management. Complete surgical excision is typically curative, and ongoing surveillance with periodic cystoscopy is recommended due to the potential for recurrence. IMT of the bladder is a rare but important differential diagnosis for bladder tumours in young patients presenting with haematuria. Timely diagnosis and surgical intervention can lead to favourable outcomes, underscoring the importance of clinical awareness.

## Linked entities

- **Diseases:** urothelial carcinoma (MONDO:0040679)

## Full-text entities

- **Genes:** ALK (ALK receptor tyrosine kinase) [NCBI Gene 238] {aka ALK1, CD246, NBLST3}
- **Diseases:** IMT (MESH:D009369), bleeding (MESH:D006470), IMT of the bladder (MESH:D001749), sarcomas (MESH:D012509), urothelial carcinoma (MESH:D014523), anaemia (MESH:D000743), spindle cell neoplasms (MESH:D002277), inflammatory (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12143931/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12143931/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12143931/full.md

---
Source: https://tomesphere.com/paper/PMC12143931