# COVID-19: Factors associated with symptoms of anxiety and depression in the ICU

**Authors:** Laura Andrea Díaz-Mayorga, Harol Giovanni Vivas-López, Claudia Consuelo Torres Contreras, Lyda Z. Rojas, Norma C. Serrano, Angie Yarlady Serrano-García, Margarita Rosa Parra Ortiz, Doris Cristina Quintero-Lesmes

PMC · DOI: 10.15649/cuidarte.3998 · Revista Cuidarte · 2025-03-26

## TL;DR

This study identifies factors linked to anxiety and depression in ICU healthcare workers during the COVID-19 pandemic in Bucaramanga.

## Contribution

The study identifies three independent risk factors for anxiety and depression in ICU healthcare staff during the pandemic.

## Key findings

- The prevalence of anxiety and depression symptoms was 8.34% among ICU healthcare workers.
- Female sex, recent COVID-19 symptoms, and working in general or COVID-19 ICUs were significant risk factors.
- The observed prevalence was lower than previously reported in the literature.

## Abstract

The COVID-19 pandemic led to a high prevalence of anxiety and depression among healthcare personnel.

To assess the prevalence and independent risk factors associated with anxiety and depression symptoms among healthcare staff working in Intensive Care Units (ICUs) during the COVID-19 pandemic in Bucaramanga and its metropolitan area.

This was an analytical cross-sectional study. Anxiety and depression were measured using the Hopkins Symptom Checklist-25 (HSCL-25). Bivariate and multivariate analyses were conducted using linear regressions to investigate associated factors.

A total of 288 people were included in the study. The prevalence of anxiety and depression symptoms was 8.34% (95% CI: 5.41-12.14%). In the bivariate analysis, six factors were associated with depression and anxiety symptoms; however, only three remained in the multivariate analysis: female sex (β=0.085, 95% CI: 0.019 - 0.151), experiencing COVID-19 symptoms in the past 14 days (β= 0.115, 95% CI: 0.024 - 0.205), and having worked in general ICUs and COVID-19 ICUs (β =0.009, 95% CI: 0.025 - 0.173).

The prevalence of anxiety and depression symptoms was considerably lower than reported in the scientific literature.

In the studied population, although the prevalence of depression and anxiety symptoms was low, three independent factors were found to be statistically associated with the presence of these mental symptoms.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** depression (MESH:D003866), Anxiety and depression (MESH:D001007), mental symptoms (MESH:D001523), COVID-19 (MESH:D000086382)

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12143909/full.md

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Source: https://tomesphere.com/paper/PMC12143909