# Asbestos-Related Pulmonary Spindle Cell Carcinoma Presenting With Ileus: An Autopsy Case Report

**Authors:** Kohei Yamane, Shiro Moriyama, Soichiro Ishikawa, Koji Fukutani, Akira Yamasaki

PMC · DOI: 10.7759/cureus.83634 · Cureus · 2025-05-07

## TL;DR

An 84-year-old man with a history of asbestos exposure developed ileus due to a rare aggressive lung cancer, highlighting the challenges in diagnosing such cases.

## Contribution

This case report presents a rare instance of asbestos-related pulmonary spindle cell carcinoma presenting with ileus.

## Key findings

- The patient had extensive pleural thickening, peritoneal dissemination, and ileus.
- Postmortem confirmed pulmonary spindle cell carcinoma with asbestos bodies in lung tissue.
- The case emphasizes the diagnostic challenges of rare thoracic malignancies with atypical presentations.

## Abstract

We present the case of an 84-year-old male with a history of occupational asbestos exposure who initially developed ileus, which was later found to be related to an aggressive pulmonary malignancy. Imaging revealed extensive pleural thickening, peritoneal dissemination, and ileus. Postmortem examination confirmed a diagnosis of pulmonary spindle cell carcinoma (PSCC), supported by immunohistochemical analysis and the presence of numerous asbestos bodies in lung tissue. This case highlights the diagnostic complexity of rare thoracic malignancies, particularly when presenting with atypical features such as ileus. Further investigation is warranted to better understand asbestos-related carcinogenesis and to improve diagnostic and treatment approaches.

## Linked entities

- **Diseases:** ileus (MONDO:0004567)

## Full-text entities

- **Diseases:** pulmonary malignancy (MESH:D009369), carcinogenesis (MESH:D063646), PSCC (MESH:D002277), pleural thickening (MESH:D010995), Ileus (MESH:D045823)
- **Chemicals:** Asbestos (MESH:D001194)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12143738/full.md

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Source: https://tomesphere.com/paper/PMC12143738