# Solitary Lichen Planus Keratosis: A Potential Clinical and Dermoscopic Mimic of Malignant Skin Neoplasm

**Authors:** Lamia Mansour Billah, Soumiya Chiheb, Mohammed Oukabli, Madiha Eljazouly

PMC · DOI: 10.7759/cureus.83630 · Cureus · 2025-05-07

## TL;DR

Solitary lichen planus keratosis can look like skin cancer, but it is benign and often goes away on its own.

## Contribution

The paper highlights SLPK as a potential mimic of skin cancer and provides clinical and dermoscopic clues for accurate diagnosis.

## Key findings

- SLPK was confirmed in two patients through histopathology despite dermoscopic features resembling malignancy.
- Dermoscopic features like orange-erythematous backgrounds and shiny white blotches were observed in non-photo-exposed areas.
- SLPK is benign and may regress spontaneously, but treatment is available for symptomatic cases.

## Abstract

Solitary lichen planus keratosis (SLPK) is a benign cutaneous lesion, often misdiagnosed due to its clinical and dermoscopic similarities to malignant conditions like basal cell carcinoma (BCC) and melanoma. We present two case reports: an 82-year-old male with an erythematous, scaly lesion on his back, and a 66-year-old female with an itchy lesion on her thigh while undergoing chemotherapy for multiple myeloma. Dermoscopic findings included orange-erythematous backgrounds with scales, sharp borders, telangiectasias, and shiny white blotches in both patients. Histopathological analysis confirmed the diagnosis of SLPK in both cases. Although lesions often regress spontaneously, treatment options such as cryotherapy and curettage are available for symptomatic cases. Dermoscopy lacks pathognomonic features, but clues such as orange areas and scales in non-photo-exposed areas may aid in diagnosis. However, due to its potential to mimic malignant lesions, histopathological confirmation remains essential for accurate diagnosis. Clinicians should be aware of SLPK’s clinical subtypes and dermoscopic features to avoid unnecessary excisions, as it is a benign condition with no carcinomatous potential.

## Linked entities

- **Diseases:** basal cell carcinoma (MONDO:0005341), melanoma (MONDO:0005105), multiple myeloma (MONDO:0009693)

## Full-text entities

- **Diseases:** telangiectasias (MESH:D013684), BCC (MESH:D002280), Malignant Skin Neoplasm (MESH:D012878), cutaneous lesion (MESH:D009059), melanoma (MESH:D008545), SLPK (MESH:D008010), multiple myeloma (MESH:D009101)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12142276/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12142276/full.md

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Source: https://tomesphere.com/paper/PMC12142276