# Translucent colonies and gram-negative diplococci: Meningococcal pneumonia masquerading as Moraxella pneumonia

**Authors:** Ryuichi Minoda Sada

PMC · DOI: 10.1016/j.idcr.2025.e02265 · IDCases · 2025-05-12

## TL;DR

A case of pneumonia caused by Neisseria meningitidis was mistaken for Moraxella pneumonia due to similar initial test results.

## Contribution

This case highlights the importance of colony appearance in differentiating meningococcal from Moraxella pneumonia.

## Key findings

- Gram-negative diplococci in sputum can be from either Neisseria meningitidis or Moraxella catarrhalis.
- N. meningitidis colonies are mucoid and translucent, while M. catarrhalis colonies are firm and white.
- Accurate diagnosis requires culture-based differentiation of these bacteria.

## Abstract

•The patient presented with pneumonia and gram-negative diplococci on sputum smear.•Neisseria meningitidis and Moraxella catarrhalis are both gram-negative diplococci.•Both bacteria can cause pneumonia but can be differentiated by culture.•Colonies of N. meningitidis are mucoid and translucent.•Colonies of M catarrhalis are firm and white.

The patient presented with pneumonia and gram-negative diplococci on sputum smear.

Neisseria meningitidis and Moraxella catarrhalis are both gram-negative diplococci.

Both bacteria can cause pneumonia but can be differentiated by culture.

Colonies of N. meningitidis are mucoid and translucent.

Colonies of M catarrhalis are firm and white.

## Linked entities

- **Diseases:** pneumonia (MONDO:0005249)
- **Species:** Neisseria meningitidis (taxon 487), Moraxella catarrhalis (taxon 480)

## Full-text entities

- **Diseases:** Moraxella pneumonia (MESH:D045828), N. meningitidis (MESH:C536108), Meningococcal pneumonia (MESH:D011014)
- **Species:** Moraxella catarrhalis (species) [taxon 480], Homo sapiens (human, species) [taxon 9606], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Neisseria meningitidis (species) [taxon 487]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12141877/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12141877/full.md

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Source: https://tomesphere.com/paper/PMC12141877