# The VITACORA- 19 and PsAID questionnaires are equally valid for assessing the impact of psoriatic arthritis on patients' quality of life

## TL;DR

The study found that the VITACORA-19 and PsAID questionnaires are similarly effective for measuring quality of life in psoriatic arthritis patients.

## Contribution

This is the first study to compare VITACORA-19 and PsAID and to define VITACORA-19 thresholds for disease activity categories.

## Key findings

- VITACORA-19 and PsAID scores showed a strong negative correlation (r: -0.7).
- VITACORA-19 thresholds were defined for low, moderate, and high DAPSA disease activity.
- A VITACORA-19 score of ≥66 corresponds to low disease impact as per PsAID.

## Abstract

Health-related quality of life (HRQoL) is an often-underestimated aspect in psoriatic arthritis (PsA). We aimed to compare the VITACORA-19 and PsAID (Psoriatic Arthritis Impact of Disease) questionnaires to assess QoL in routine PsA management.

Cross-sectional analysis of a randomly selected PsA population. Disease activity was estimated using the DAPSA (Disease Activity score for PsA) index and HRQoL using the VITACORA-19 and PsAID. The construct validity of VITACORA-19 was analysed (Pearson correlation and ROC curves).

Forty-five patients were included, 24 men and 21 women, mean age 55 ± 13 years, mean disease duration 8.2 ± 6.1 years. Most patients showed adequate disease control, median DAPSA 11.3 (IQR: 8.0–19.3), median PsAID 2.7 (IQR: 1.1–5.0). VITACORA-19 scores ranged from 6 to 94. The correlation between VITACORA-19 and PsAID was high, r: -0.7 (95%CI: -0.84 to -0.46), p < 0.0001. A VITACORA-19 score in the range of 6–29 corresponded to high DAPSA disease activity, a range of 30–44 corresponded to moderate DAPSA activity and a range of 45–95 corresponded to low DAPSA activity. The cut-off for an acceptable symptomatic state (PsAID < 4) corresponded to a VITACORA-19 score ≥ 66 with an area under the ROC curve of 0.85 (95%CI: 0.71–0.98).

This is the first study comparing the VITACORA-19 and PsAID questionnaires. Either of the two questionnaires could be used to assess HRQoL in PsA. For the first time, VITACORA-19 thresholds are defined that identify the different DAPSA activity categories. A VITACORA-19 score ≥ 66 could be an appropriate treatment target.

Key Points• Health-related quality of life (HRQoL) is an often-underestimated aspect in psoriatic arthritis (PsA).• The PsAID and VITACORA-19 questionnaires offer similar performance for assessing HRQoL in PsA.• A VITACORA-19 ≥ 66 identifies the low disease impact state according to the PsAID.• VITACORA-19 thresholds identifying DAPSA categories are reported.

• Health-related quality of life (HRQoL) is an often-underestimated aspect in psoriatic arthritis (PsA).

• The PsAID and VITACORA-19 questionnaires offer similar performance for assessing HRQoL in PsA.

• A VITACORA-19 ≥ 66 identifies the low disease impact state according to the PsAID.

• VITACORA-19 thresholds identifying DAPSA categories are reported.