# Measurement of U and Pu isotopic ratio in environmental samples through MC-ICP-MS integrated to an automated microfluidic column

## TL;DR

A new microfluidic system with MC-ICP-MS enables efficient and low-volume analysis of uranium and plutonium isotopes in environmental samples.

## Contribution

The integration of a microfluidic system with MC-ICP-MS enables real-time Pu and U isotope ratio measurements with reduced sample and reagent volumes.

## Key findings

- The system reduces sample volume to less than 80 µL.
- Analyte quantities are reduced from micrograms to less than nanograms.
- The method is less resource-intensive and generates less waste.

## Abstract

Accurate identification of isotopes and elements of uranium (U) and plutonium (Pu) in environmental samples from the nuclear fuel cycle is essential for environmental monitoring and safeguarding. A novel microfluidic system coupled with a multi-collecting inductively coupled plasma mass spectrometer (MC-ICP-MS) allows the measurement Pu and U isotope ratios in real time. The application reduces the sample volume required to less than 80 µL with required quantities of analytes being reduced from the conventional micrograms to less than nanograms. This reduction in sample and reagent volume makes the analytical process less resource-intensive and generates less waste; a significant benefit for safer and more efficient analysis operations.