# Rupture of the Abdominal Aorta without Aneurysm Associated with Giant Cell Arteritis: A Case Report

**Authors:** Akito Kuwano, Masaru Yoshikai, Satoshi Ohtsubo, Kiyokazu Koga, Nozomi Yoshida, Naoyo Nishida

PMC · DOI: 10.3400/avd.cr.25-00010 · Annals of Vascular Diseases · 2025-06-03

## TL;DR

A 67-year-old woman experienced a rare case of abdominal aortic rupture linked to giant cell arteritis, not caused by an aneurysm.

## Contribution

This case report highlights a rare association between giant cell arteritis and aortic rupture without aneurysm.

## Key findings

- Contrast-enhanced CT showed retroperitoneal hematoma and aortic contrast leakage.
- Histopathology confirmed giant cell arteritis in the resected aortic wall.
- No aneurysmal changes were observed in the abdominal aorta.

## Abstract

We report a case of an abdominal aortic rupture without aneurysm associated with giant cell arteritis. A 67-year-old woman presented with lower back pain. Contrast-enhanced computed tomography revealed a massive retroperitoneal hematoma with contrast leakage from the abdominal aorta, suggestive of abdominal aortic rupture. During emergency surgery, a rupture site was identified on the anterior wall of the abdominal aorta, while no aneurysmal changes or dilatation of the abdominal aorta were observed. Histopathological examination of the resected aortic wall revealed infiltration of giant cells positive for CD68, leading to the diagnosis of giant cell arteritis.

## Linked entities

- **Diseases:** giant cell arteritis (MONDO:0008538)

## Full-text entities

- **Genes:** CD68 (CD68 molecule) [NCBI Gene 968] {aka GP110, LAMP4, SCARD1}
- **Diseases:** Giant Cell Arteritis (MESH:D013700), Aneurysm (MESH:D000783), back pain (MESH:D001416), hematoma (MESH:D006406), abdominal aortic rupture (MESH:D001019)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12140923/full.md

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Source: https://tomesphere.com/paper/PMC12140923