This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis
Mediators of Inflammation

Abstract
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Taxonomy
TopicsBioactive natural compounds · Neuroinflammation and Neurodegeneration Mechanisms · Natural product bioactivities and synthesis
RETRACTION: S. Zhang, Q.-C. Kang, Y. Xu, G.-X. Zhang, and L. Zhu, “Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis,” Mediators of Inflammation 2013, no. 1 (2013): 1–10, https://doi.org/10.1155/2013/736085.
The above article, published online on 08 September 2013 in Wiley Online Library (wileyonlinelibrary.com), has been retracted following the agreement of the journal's Chief Editor, Anshu Agrawal; and John Wiley & Sons Ltd.
The retraction has been agreed following an investigation of the concerns raised by Elizabeth Bik on PubPeer [1], which identified concerns regarding Figures 2a and 6a.
Specifically, similarity has been identified between the features of several panels of Figure 2a with Figure 1c of [2]. In addition, multiple similarities were identified between the features of different panels in Figure 6a.
As a result of the investigation, the data and conclusions of this article are considered unreliable.
The authors had been informed of this retraction but did not provide a response.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Elizabeth M Bik Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis Pub Peer July 2022, https://pubpeer.com/publications/2FD 713B 2211 B 5942 D 20F 829EDAA 56C
- 2Kan Q.-C. Zhang S. Xu Y.-M. Zhang G.-X. Zhu L. RETRACTED: Matrine Regulates Glutamate-Related Excitotoxic Factors in Experimental Autoimmune Encephalomyelitis Neuroscience Letters 2014560929710.1016/j.neulet.2013.12.0312-s 2.0-8489165257324368216 · doi ↗ · pubmed ↗
