# Giant malignant phyllodes tumor: A case report

**Authors:** Daniela Kerguelen Murcia, Andrea Tenreiro, Jennifer A. Kohlnhofer, Celeste Wagner, Flavia Posleman Monetto

PMC · DOI: 10.1016/j.radcr.2025.04.078 · Radiology Case Reports · 2025-05-13

## TL;DR

This case report describes a rare giant malignant phyllodes tumor in a 53-year-old woman and outlines its clinical features, diagnosis, and treatment.

## Contribution

The novelty lies in presenting a rare case of giant malignant phyllodes tumor with comprehensive clinical and radiological details.

## Key findings

- The tumor was diagnosed via biopsy showing leaf-like architecture and stromal cellularity.
- Ultrasound and mammography findings were consistent with phyllodes tumor characteristics.
- The patient underwent right mastectomy as treatment.

## Abstract

Phyllodes tumor is a rare fibroepithelial breast mass that typically manifests as a painless, multinodular breast tumor. One characteristic feature of phyllodes tumors is that they tend to increase in size rapidly over time unlike fibroadenomas. On ultrasound, they typically appear as a hypoechoic solid mass that may contain cystic components. On mammography, they appear hyperdense. Definitive diagnosis requires biopsy, with histological findings of leaf-like architecture and stromal cellularity. This report presents a case of giant malignant phyllodes tumor in a 53-year-old female who underwent right mastectomy and provides an overview of its clinical presentation, diagnostic workup, radiologic imaging findings, and management.

## Linked entities

- **Diseases:** phyllodes tumor (MONDO:0005078), breast tumor (MONDO:0007254)

## Full-text entities

- **Diseases:** fibroadenomas (MESH:D018226), fibroepithelial breast mass (MESH:D061325), malignant phyllodes tumor (MESH:C549759), breast tumor (MESH:D001943), Phyllodes tumor (MESH:D003557)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12139673/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12139673/full.md

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Source: https://tomesphere.com/paper/PMC12139673