# Acute macular neuroretinopathy after Covid 19 in an eye with a congenital retinal macrovessel – a case report

**Authors:** A. Vienne-Jumeau, E. Souied, F. Amoroso

PMC · DOI: 10.1016/j.ajoc.2025.102349 · American Journal of Ophthalmology Case Reports · 2025-05-06

## TL;DR

A 48-year-old woman developed acute macular neuroretinopathy in an eye with a retinal macrovessel following a Covid-19 infection.

## Contribution

This is the first reported case of AMN occurring alongside a congenital retinal macrovessel after a Covid-19 infection.

## Key findings

- The patient presented with a 10-day scotoma and petaloid brown lesions in the right eye.
- Multimodal imaging confirmed AMN with defects in the deep capillary plexus.
- The authors suggest that the combination of abnormal retinal vasculature and Covid-19 may have caused the AMN.

## Abstract

To present a case of an acute macular neuroretinopathy (AMN) occurring after Covid 19 infection in an eye with a retinal macrovessel.

We report a case of a 48-year-old woman who presented to our center with a 10-day scotoma in her right eye, in the context of a recently diagnosed Covid 19 infection. The funduscopy demonstrated a petaloid brown lesions temporal to the fovea in the right eye. A retinal macrovessel, passing adjacent to the lesions was also present. The left eye was normal. Multimodal imaging confirmed the diagnostic of AMN and optical coherence tomography angiography showed defects in the deep capillary plexus colocalizing with the lesions.

Ischemic events have been known to complicate macrovessel, and we reckon that the occurrence of AMN in this patient could have been the resultant of the conjunction of Covid 19 infection and abnormal retinal vasculature.

Claims of Priority statement: After conducting a literature review on September 20, 2024, using PubMed, Google Scholar, and Medline with the keywords "macrovessel" and ("macular neuroretinopathy" or "AMN"), we found no prior reports of the concomitant occurrence of a congenital macrovessel and macular neuroretinopathy.

## Linked entities

- **Diseases:** Covid 19 (MONDO:0100096), acute macular neuroretinopathy (MONDO:0044627), scotoma (MONDO:0004758)

## Full-text entities

- **Diseases:** congenital retinal macrovessel (MESH:D012173), Covid 19 (MESH:D000086382), scotoma (MESH:D012607), AMN (MESH:D000080363)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12139215/full.md

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Source: https://tomesphere.com/paper/PMC12139215