# Severe E-Cigarette-Induced Esophagitis in a Patient With Eosinophilic Esophagitis: A Case Report

**Authors:** Larissa A Lucena, Paulo César da Silva, Verônica S Vale, Sílvio José L Dantas, Rodrigo A Oliveira

PMC · DOI: 10.7759/cureus.83563 · Cureus · 2025-05-06

## TL;DR

A man with a history of allergies and esophageal issues developed severe esophagitis after vaping, showing a possible link between e-cigarettes and esophageal damage.

## Contribution

Highlights a rare case linking e-cigarette use to severe esophagitis in a patient with pre-existing conditions.

## Key findings

- A 24-year-old man developed severe esophageal ulcerations and necrosis after a week of vaping.
- Follow-up endoscopy showed diverticular formations and friable lesions despite treatment.
- The case suggests a potential association between vaping and ulcerative esophagitis in vulnerable individuals.

## Abstract

Chemical esophagitis, a rare and potentially life-threatening condition, was diagnosed in a 24-year-old man with food allergies, presumed IgA nephropathy, eosinophilic esophagitis (EoE), and electronic cigarette (e-cigarette) use. After a week of vaping, he developed severe dysphagia, and endoscopy revealed extensive esophageal ulcerations and necrosis. Treatment included total parenteral nutrition, esomeprazole, and sucralfate. Follow-up endoscopy showed diverticular formations and friable lesions. This case underscores the emerging link between vaping and ulcerative esophagitis, especially in patients with pre-existing conditions, highlighting the need for early diagnosis and further research to understand and manage this association.

## Linked entities

- **Diseases:** eosinophilic esophagitis (MONDO:0005361), IgA nephropathy (MONDO:0005342)

## Full-text entities

- **Diseases:** EoE (MESH:D057765), Chemical (MESH:D019966), food allergies (MESH:D005512), Esophagitis (MESH:D004941), necrosis (MESH:D009336), dysphagia (MESH:D003680), IgA nephropathy (MESH:D005922)
- **Chemicals:** sucralfate (MESH:D013392), esomeprazole (MESH:D064098)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12138953/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12138953/full.md

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Source: https://tomesphere.com/paper/PMC12138953