# Histological and Morphological Evaluation of Exfoliated Silver Diamine Fluoride-Treated Carious Primary Teeth

**Authors:** Mridula Goswami, Riya Marie Johnson, Babita Jangra

PMC · DOI: 10.7759/cureus.83554 · Cureus · 2025-05-06

## TL;DR

This study examines how silver diamine fluoride affects carious primary teeth at a microscopic level, showing its effectiveness but also noting discoloration as a drawback.

## Contribution

The paper provides new histological and morphological insights into the effects of silver diamine fluoride on carious dentin in primary teeth.

## Key findings

- Silver diamine fluoride effectively arrests caries in primary teeth.
- Application of SDF leads to pronounced discoloration due to silver particles in dentinal tubules.
- Periodic re-application of SDF enhances its caries-arresting potential.

## Abstract

Silver diamine fluoride (SDF) is a minimally invasive treatment modality that has gained attention in recent years owing to its remineralizing capability. However, there is limited research on its effect at a microscopic level. This case series presents three cases of exfoliated primary teeth where histologic and morphological analysis was performed after a single application of SDF on carious dentin. This paper provides valuable insights into the long-term and sustained effectiveness of SDF, making it a cost-effective treatment for young, uncooperative children including those with special health care needs. In addition, it also highlights that periodic re-application of SDF can enhance the overall caries-arresting potential. However, despite the clinical success, the inclusion of silver particles deep within the dentinal tubules results in pronounced discoloration, which is a significant drawback of SDF. Future research has to be directed toward innovative techniques to overcome discoloration while maintaining its efficacy.

## Linked entities

- **Chemicals:** silver diamine fluoride (PubChem CID 161820), SDF (PubChem CID 46173033)

## Full-text entities

- **Diseases:** caries (MESH:D003731)
- **Chemicals:** silver (MESH:D012834), SDF (MESH:C024633)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12138747/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12138747/full.md

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Source: https://tomesphere.com/paper/PMC12138747