# Reducing Time to Analgesia for Sickle Cell Pain Episode Treatment in the Pediatric Emergency Department

**Authors:** Amelia F. Wong, Jaime K. Otillio, Abby K. Fahnestock, Christine M. Smith, Michael R. DeBaun, Emmanuel Volanakis, Lacey Noffsinger, Jeannie Byrd, S. Barron Frazier

PMC · DOI: 10.1097/pq9.0000000000000821 · Pediatric Quality & Safety · 2025-06-04

## TL;DR

This study aimed to reduce the time it takes to give pain medicine to children with sickle cell disease in the emergency department.

## Contribution

The study implemented a standardized order set and home action plan integration to improve analgesia delivery times in pediatric SCD patients.

## Key findings

- Time from ED rooming to analgesia decreased from 50 to 32 minutes after interventions.
- Pain assessments in the first 2 hours increased from 2.2 to 2.7 with order set use.
- ED length of stay remained unchanged despite process improvements.

## Abstract

Pain episodes are the most common emergency department (ED) presentation for patients with sickle cell disease (SCD). Prompt pain medication and frequent pain assessments are recommended. Our SMART aim was to reduce the time from ED rooming to first analgesia administration for children presenting with SCD pain from 50 to less than 30 minutes by June 2024.

Children presenting to the ED with a diagnosis of SCD requiring opioids for pain were included. The primary outcome was time from rooming to analgesia. A key driver diagram, developed by a multidisciplinary team, informed our interventions and then implemented through plan-do-study-act cycles. Statistical process control charts were used to analyze data with Nelson rules to detect special cause variation. Secondary measures included frequency of pain assessments in the first 2 hours and ED length of stay.

From July 2020 to June 2024, there were 447 eligible encounters. Baseline data (n = 143) revealed an average time from ED rooming to analgesia of 50 minutes. Following interventions, including order set implementation, multidisciplinary collaboration, and incorporating the home action plan in the ED, special cause variation was detected with a centerline shift to 32 minutes. The median number of pain assessments in the first 2 hours of arrival improved from 2.2 to 2.7 with order set utilization. ED length of stay remained unchanged.

Standardizing care with an order set increased the number of pain assessments. Incorporation of the SCD home pain action plan into the ED treatment pathway decreased the time to analgesia.

## Linked entities

- **Diseases:** sickle cell disease (MONDO:0011382), SCD (MONDO:0000359)

## Full-text entities

- **Diseases:** Analgesia (MESH:D000699), Pain (MESH:D010146), SCD (MESH:D000755)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12136660/full.md

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Source: https://tomesphere.com/paper/PMC12136660