# Esophageal Granular Cell Tumor Associated With Eosinophilic Gastrointestinal Disease

## TL;DR

This paper reports the first case of an esophageal granular cell tumor in a patient with a long history of eosinophilic gastrointestinal disease.

## Contribution

The paper presents the first documented case linking esophageal granular cell tumor with active eosinophilic gastrointestinal disease.

## Key findings

- The patient had a long history of eosinophilic gastrointestinal disease before being diagnosed with an esophageal granular cell tumor.
- This case suggests a potential association between eosinophilic inflammation and granular cell tumor development in the esophagus.

## Abstract

Granular cell tumors (GCTs) are typically benign lesions that can occur in the gastrointestinal tract. Eosinophilic gastrointestinal disease, including eosinophilic esophagitis (EoE), is an immune-mediated condition characterized by eosinophil-predominant inflammation in the gastrointestinal tract. We review previously reported cases of EoE associated with GCTs. To our knowledge, we present the first case of esophageal GCT in a patient with a long history of eosinophilic gastrointestinal disease and likely several years of active EoE before esophageal GCT diagnosis.