# EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH SYSTEMIC SCLEROSIS TREATED AT A QUATERNARY HOSPITAL IN THE STATE OF SÃO PAULO

**Authors:** Pedro Henrique de Magalhães Tenório, Rafaella Camilo de Oliveira, Matheus Portilho Pinto Ribeiro, Ramon Alves Queiroz, Marcos Felipe Marcatto de Abreu

PMC · DOI: 10.1590/1413-785220253302e287081 · Acta Ortopedica Brasileira · 2025-06-02

## TL;DR

This study describes the characteristics of systemic sclerosis patients treated at a hospital in São Paulo, focusing on age, gender, and disease patterns.

## Contribution

The study provides an updated epidemiological profile of systemic sclerosis patients in a specific Brazilian hospital setting.

## Key findings

- The average age of patients was 49.96 years, with a predominance of women.
- A significant correlation was found between Rodnan score and HAQ/SHAQ scores.
- The limited form of the disease was more prevalent in women compared to men.

## Abstract

To report the profile of patients diagnosed with systemic sclerosis and monitored in a four-year hospital in São Paulo.

Observational study with 51 patients, mostly composed of women. Descriptive statistics such as mean age, proportions (sex, ethnicity, form of the disease), and correlations between functional scores (HAQ, SHAQ, and Rodnan score) were extracted.

The average age found was 49.96 ± 12.01 years. The time since diagnosis was 11.19 ± 10.16 years. When separated by sex, 25% of men presented the limited form, while 65.9% of women presented the localized form. There was a statistically significant correlation (p-value<0.01) between the Rodnan score and the HAQ score, with a value of 0.36 (CI: 0.09-0.58), as well as with the SHAQ score (value of 0.33; CI: 0.05-0.55, p-value=0.01). When evaluating the correlation between the Rodnan score and the Cochin functional scale, there was a statistically significant correlation (p-value<0.01), with a value of 0.38 (0.12-0.58).

According to the literature, this study showed the highest prevalence in women, and the predominant form is limited. 
Level of Evidence II; Cohort Study.

## Linked entities

- **Diseases:** systemic sclerosis (MONDO:0005100)

## Full-text entities

- **Diseases:** SYSTEMIC SCLEROSIS (MESH:D012595)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12136614/full.md

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Source: https://tomesphere.com/paper/PMC12136614