# Plummer-Vinson Syndrome in a Pakistani Woman: A Case Report

## TL;DR

A 36-year-old Pakistani woman with long-term swallowing difficulties and severe anemia was diagnosed with Plummer-Vinson Syndrome and successfully treated with iron supplements.

## Contribution

This case report adds a rare clinical example of PVS in a Pakistani patient, emphasizing the importance of early diagnosis and iron therapy.

## Key findings

- The patient exhibited classic PVS symptoms including dysphagia, cheilitis, and severe iron deficiency anemia.
- Endoscopic and radiographic findings confirmed esophageal web and stenosis consistent with PVS.
- Symptoms resolved following iron supplementation, highlighting effective treatment for PVS.

## Abstract

Plummer-Vinson Syndrome (PVS) is characterized by dysphagia, iron deficiency anemia, and esophageal web formation. We discuss the case of a 36-year-old woman from Pakistan who presented with dysphagia for approximately 10 years, cheilitis, and glossitis. Barium esophagram was consistent with a proximal esophageal web. Esophagogastroduodenoscopy (EGD) found a cricopharyngeal stenosis requiring multiple dilations. Initial hemoglobin was 5.0 g/dL, mean corpuscular volume 51.6 fL, ferritin level 1 ng/mL, and iron level <10 μg/dL. She was diagnosed with PVS, treated with iron supplementation, and had resolution of symptoms and dysphagia.