# Present or Absent: Risks and protective factors of sudden infant death syndrome (SIDS) in the Zambian context

**Authors:** Ethan M. Zulu, Lawrence Mwananyanda, Rachel C. Pieciak, Leah S. Forman, Janaki Shah, Tim Heeren, Christopher J. Gill, Roma Chilengi, Barbara Payne-Lohman, Cassandra R. Duffy, Godwin Osei-Poku, Donald M. Thea, Somwe Wa Somwe, Julie M. Herlihy

PMC · DOI: 10.21203/rs.3.rs-6427293/v1 · Research Square · 2025-05-13

## TL;DR

This study explores risk and protective factors for sudden infant death syndrome in Zambia, highlighting common sleep practices and socioeconomic challenges.

## Contribution

The study provides new insights into SUID risk factors in a low-income Zambian population, emphasizing culturally relevant public health strategies.

## Key findings

- Most infants sleep in prone or side positions and share sleep surfaces with caregivers.
- Breastfeeding is highly prevalent and acts as a protective factor.
- Low birthweight and prematurity are significant non-modifiable risk factors.

## Abstract

Despite a reduction in Sudden Unexplained Infant Death (SUID) in high-income countries, the incidence of SUID and the prevalence of its risk and protective factors remain poorly understood in Zambia due to limited research. The aim of our study was to describe the infant sleep positions and sleep environments in an urban Zambian population to gain a better understanding of the modifiable risk factors for SUID.

Data from the Zambian Infant Cohort Study (ZICS), a prospective birth cohort, were collected to describe infant sleep practices in Chawama, a densely populated peri-urban community in Lusaka, Zambia. During the 20-week study visit a structured questionnaire was administered to obtain data about the sleeping and environmental risks associated with SUID.

Data were collected from 596 caregivers and 605 infants. Only 6.4% of caregivers did attain an education beyond secondary school, and a significant proportion of infants (20.2%) had low birth weights, with 10.7% of infants confirmed by ultrasound as preterm. Furthermore, 96.5% of infants were placed to sleep on their side or in a prone position, and 98.2% of infants shared a sleep surface with their caregiver. Breastfeeding, a protective factor, was highly prevalent, with 90.2% of infants receiving some form of breastfeeding at the 24-week visit.

The results of this study show that both modifiable (bed-sharing and prone sleep position) and non-modifiable risk factors (low birthweight and prematurity) of SUID are prevalent in this low socioeconomic setting in Zambia. Public health strategies to prevent SUID will need to be innovative and culturally congruent in addressing modifiable risks, such as bedsharing, in settings where there is a lack of space.

Trial number: 1R01HD094650

## Linked entities

- **Diseases:** Sudden Infant Death Syndrome (MONDO:0010086)

## Full-text entities

- **Diseases:** SIDS (MESH:D013398), prematurity (MESH:C536271)

## Full text

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12136194/full.md

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Source: https://tomesphere.com/paper/PMC12136194