# Rare case of a massive anterior mediastinal schwannoma causing cardiac compression with concurrent cervical spine lesion causing spinal cord compression

**Authors:** Sajjaad H. Samat, Bradley Ruehle, Emily Sheldon, Hisham Qandeel

PMC · DOI: 10.1186/s13019-025-03452-4 · Journal of Cardiothoracic Surgery · 2025-06-04

## TL;DR

A rare case of a large anterior mediastinal schwannoma causing heart compression and a cervical spine lesion leading to spinal cord compression is reported.

## Contribution

This case highlights the rare occurrence of an anterior mediastinal schwannoma with a concurrent symptomatic cervical lesion.

## Key findings

- The schwannoma caused cardiac compression due to its large size in the anterior mediastinum.
- A concurrent cervical spine lesion resulted in right-sided weakness due to spinal cord compression.
- Such combined presentations are extremely rare and underreported in the literature.

## Abstract

Schwannoma is the most common neurogenic tumor in the posterior mediastinum, however it is rarely found in the anterior mediastinum (Mediastinum 4, 2020; Radiat Med 13(4):175-7). We report a large anterior mediastinal schwannoma causing cardiac compression along with a concurrent cervical spine lesion causing right-sided weakness. Current literature having only a few case reports describing an anterior location for this neoplasm and even rarer to have a concurrent symptomatic cervical lesion. We present this case to highlight this rare finding and increase awareness of this potential diagnosis.

## Linked entities

- **Diseases:** schwannoma (MONDO:0002546)

## Full-text entities

- **Diseases:** neoplasm (MESH:D009369), cervical lesion (MESH:D002575), spinal cord compression (MESH:D013117), weakness (MESH:D018908), anterior mediastinal schwannoma (MESH:D008480), cardiac compression (MESH:D009408), Schwannoma (MESH:D009442)

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12135393/full.md

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Source: https://tomesphere.com/paper/PMC12135393