# Sclerosing Angiomatoid Nodular Transformation of the Spleen: Multimodality Imaging Features

**Authors:** Burhan Vural, Ihsaniye Suer Dogan, Berna Turhan, Sümeyya Duran Kaymak, Mustafa Hulusi Kurt, Rasime Pelin Kavak

PMC · DOI: 10.7759/cureus.83488 · Cureus · 2025-05-05

## TL;DR

This paper presents a case of a rare benign spleen condition in a woman with thyroid cancer, managed through surgery and diagnosed postoperatively.

## Contribution

The paper highlights the radiological features of SANT to improve its differential diagnosis in cancer patients.

## Key findings

- SANT was diagnosed in a patient with metastatic thyroid cancer and an undiagnosed splenic mass.
- Laparoscopic splenectomy effectively managed the condition and confirmed the diagnosis postoperatively.

## Abstract

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign lesion. This report presents the case of a middle-aged woman with asymptomatic SANT of the spleen, complicated by metastatic papillary thyroid carcinoma and an undiagnosed splenic mass. The condition was effectively managed through laparoscopic splenectomy, with a definitive diagnosis confirmed postoperatively. This case aims to contribute to enhancing the differential diagnosis of SANT by highlighting its radiological features, particularly in patients undergoing follow-up for malignancy.

## Linked entities

- **Diseases:** papillary thyroid carcinoma (MONDO:0005075)

## Full-text entities

- **Diseases:** splenic mass (MESH:D013158), papillary thyroid carcinoma (MESH:D000077273), malignancy (MESH:D009369), SANT (MESH:D012598)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12134817/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12134817/full.md

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Source: https://tomesphere.com/paper/PMC12134817