# A Case of Diabetic Ketoacidosis-Induced Cardiomyopathy

**Authors:** Chelsea Crosby, Lei Gao

PMC · DOI: 10.7759/cureus.83472 · Cureus · 2025-05-04

## TL;DR

A patient with diabetic ketoacidosis developed a reversible heart condition, suggesting a metabolic cause rather than emotional or physical stress.

## Contribution

This case highlights a novel metabolic trigger for stress-like cardiomyopathy unrelated to typical stressors.

## Key findings

- The patient's cardiomyopathy was linked to diabetic ketoacidosis, not emotional or physical stress.
- Echocardiogram and catheterization showed no coronary abnormalities, pointing to a metabolic cause.
- The case suggests a distinct mechanism for DKA-induced cardiomyopathy.

## Abstract

Stress cardiomyopathy is a reversible syndrome that is usually triggered by emotional and physical stressors. We describe a patient who was admitted with diabetic ketoacidosis (DKA) and found to have metabolic-induced cardiomyopathy. The echocardiogram primarily revealed hypokinesis in the mid-segments, and left heart catheterization showed angiographically normal-appearing coronary vessels. The patient did not have significant emotional or physical stressors but did have a significant metabolic derangement. We suspect that the underlying mechanism of DKA-induced cardiomyopathy may differ from that of stress cardiomyopathy. Therefore, further observation and investigation are warranted.

## Linked entities

- **Diseases:** diabetic ketoacidosis (MONDO:0012819), stress cardiomyopathy (MONDO:0019018)

## Full-text entities

- **Diseases:** Stress cardiomyopathy (MESH:D054549), Cardiomyopathy (MESH:D009202), DKA (MESH:D016883)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12134704/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12134704/full.md

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Source: https://tomesphere.com/paper/PMC12134704