# Advancing AAV technology: From capsid design to scalable manufacturing

**Authors:** Daniel Stone, Mario Mietzsch, Giuseppe Ronzitti

PMC · DOI: 10.1016/j.omtm.2025.101477 · Molecular Therapy. Methods & Clinical Development · 2025-05-07

## Full-text entities

- **Genes:** SNAP23 (synaptosome associated protein 23) [NCBI Gene 8773] {aka HsT17016, SNAP-23, SNAP23A, SNAP23B}, SNAR-E (small NF90 (ILF3) associated RNA E) [NCBI Gene 100170220], STX7 (syntaxin 7) [NCBI Gene 8417], FAP (fibroblast activation protein alpha) [NCBI Gene 2191] {aka DPPIV, FAPA, FAPalpha, SIMP}
- **Diseases:** neuromuscular diseases (MESH:D009468), MTMCD (MESH:D002658), cancer (MESH:D009369), genetic diseases (MESH:D030342)
- **Chemicals:** O-glycans (-), amino acids (MESH:D000596)
- **Species:** Homo sapiens (human, species) [taxon 9606], adeno-associated virus 2 (no rank) [taxon 10804], Adeno-associated virus (species) [taxon 272636], Ascochyta sp. AV8 (species) [taxon 372030], Acinetobacter calcoaceticus (species) [taxon 471]
- **Cell lines:** Sf9 — Spodoptera frugiperda (Fall armyworm), Spontaneously immortalized cell line (CVCL_0549), HEK293 — Homo sapiens (Human), Transformed cell line (CVCL_0045)

## Full text

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12134569/full.md

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Source: https://tomesphere.com/paper/PMC12134569