# Cryoablation as local therapy in patients with locally recurrent thyroid cancer: Two case reports

**Authors:** Sorina R. Simon, Tim Lubbers, Sanne Engelen, Sanne W. de Boer, Christiaan van der Leij

PMC · DOI: 10.1016/j.radcr.2025.04.065 · Radiology Case Reports · 2025-05-08

## TL;DR

Cryoablation is presented as a promising minimally invasive treatment for locally recurrent thyroid cancer, with successful outcomes in two case reports.

## Contribution

The paper contributes two case reports demonstrating the feasibility of cryoablation for thyroid cancer recurrence.

## Key findings

- Follow-up ultrasound showed complete involution in one patient after cryoablation.
- The second patient experienced a 73% volume reduction of the lesion.
- No delayed complications were observed in either case.

## Abstract

The local surgical treatment of thyroid cancer recurrence poses significant challenges, particularly when addressing areas affected by extensive scar tissue. Cryoablation of local recurrences might be a promising minimally invasive alternative, especially for patients who are not ideal surgical candidates or prefer nonsurgical interventions. This report discusses 2 cases of recurrent thyroid cancer successfully managed with curative intent cryoablation. Follow-up ultrasound revealed complete involution in the first patient, and 73% volume reduction of the lesion in the second patient. No delayed complications were observed. It underlines the potential of cryoablation as a feasible treatment option for local recurrence of thyroid cancer and advocates for future research to better define its role within thyroid cancer management protocols.

## Linked entities

- **Diseases:** thyroid cancer (MONDO:0002108)

## Full-text entities

- **Diseases:** thyroid cancer (MESH:D013964)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12134475/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12134475/full.md

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Source: https://tomesphere.com/paper/PMC12134475