# Sugar cane extracts as natural taste modulators: potential for sugar reduction in beverages and beyond

**Authors:** Thalia Marina Llalla Vidal, Gregor Macnab, Shane Mitchell, Matthew Flavel

PMC · DOI: 10.3389/fnut.2025.1603101 · Frontiers in Nutrition · 2025-05-20

## TL;DR

This paper reviews how sugar cane extracts can improve the taste of low-sugar beverages, helping reduce added sugars without sacrificing flavor.

## Contribution

The paper highlights sugar cane extracts as a novel natural solution for sugar reduction through multimodal taste modulation.

## Key findings

- Sugar cane extracts enhance sweetness and mask bitterness in reduced-sugar products.
- They improve mouthfeel and consumer acceptability of low-calorie sweetened beverages.
- The extracts interact with sweet and bitter taste receptors to modulate flavor perception.

## Abstract

The reduction of added sugars in food and beverage products has become a global health priority, driven by rising rates of obesity, diabetes, and cardiovascular disease. Yet, achieving sugar reduction without compromising taste remains a major challenge for manufacturers. This review explores the potential of sugar cane extracts—specifically Modulex™, as natural taste modulators capable of enhancing sweetness, masking bitterness, and improving mouthfeel in reduced-sugar formulations. Derived from Saccharum officinarum, these extracts contain a complex mixture of sugars, polyphenols, amino acids, and minerals that act through multimodal sensory pathways, including interactions with sweet (T1R2/T1R3) and bitter (TAS2R) taste receptors. Evidence from sensory studies demonstrates that sugar cane extracts can significantly improve the flavor profile and consumer acceptability of beverages sweetened with natural or artificial low-calorie sweeteners. This review discusses the biochemical basis of these effects, their regulatory positioning, and their implications for product development aligned with clean-label trends and public health goals. Sugar cane extracts represent a promising ingredient for next-generation sugar reduction strategies that balance health, taste, and consumer preference.

## Linked entities

- **Proteins:** TAS1R2 (taste 1 receptor member 2), TAS1R3 (taste 1 receptor member 3), LOC100976598 (taste receptor type 2 member 62)
- **Diseases:** obesity (MONDO:0011122), diabetes (MONDO:0005015), cardiovascular disease (MONDO:0004995)
- **Species:** Saccharum officinarum (taxon 4547)

## Full-text entities

- **Diseases:** cardiovascular disease (MESH:D002318), obesity (MESH:D009765), diabetes (MESH:D003920), bitterness (MESH:D013651)
- **Chemicals:** Modulex (-), amino acids (MESH:D000596), minerals (MESH:D008903), sugar (MESH:D000073893), polyphenols (MESH:D059808)
- **Species:** Saccharum officinarum (noble cane, species) [taxon 4547]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12131862/full.md

## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12131862/full.md

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Source: https://tomesphere.com/paper/PMC12131862