# Surgical Management of a Spontaneous Hepatocellular Carcinoma Rupture in a Non-cirrhotic Liver: A Case Report

**Authors:** Maria Isabel Manso, Henrique Morais, Ruben Martins, Mafalda Machado, Gildasio Martins Dos Santos

PMC · DOI: 10.7759/cureus.83441 · Cureus · 2025-05-04

## TL;DR

A rare case of liver cancer rupture in a patient without liver disease is successfully treated with surgery.

## Contribution

Presents a rare clinical case of spontaneous HCC rupture in a non-cirrhotic liver and its successful surgical management.

## Key findings

- A 78-year-old man with no liver disease history had a ruptured exophytic HCC lesion in hepatic segment II.
- Successful segment II resection was performed after stabilization, with uneventful postoperative recovery.
- Histopathology confirmed moderately differentiated HCC in a non-cirrhotic liver.

## Abstract

Spontaneous rupture of hepatocellular carcinoma (HCC) is an uncommon and life-threatening condition that poses significant diagnostic and therapeutic challenges. This report describes the case of a 78-year-old man with no prior history of liver disease who presented with acute abdominal pain and hemoperitoneum. Imaging revealed a ruptured exophytic HCC lesion in hepatic segment II, which was confirmed during laparotomy. The patient underwent successful segment II resection following stabilization, and histopathological analysis confirmed a moderately differentiated HCC in a non-cirrhotic liver. The postoperative course was uneventful. This case highlights the importance of timely diagnosis, tailored management strategies, and multidisciplinary care in addressing the complexities of spontaneous HCC rupture, particularly in patients without underlying liver disease.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Diseases:** liver disease (MESH:D008107), HCC rupture (MESH:D012421), HCC (MESH:D006528), cirrhotic Liver (MESH:D008103), abdominal pain (MESH:D015746), hemoperitoneum (MESH:D006465)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12130909/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12130909/full.md

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Source: https://tomesphere.com/paper/PMC12130909