# Facial Affect Recognition and Executive Function Abnormalities in ADHD Subjects: An ERP Study

## TL;DR

This study explores how ADHD affects brain responses related to attention and emotion recognition using ERP measurements.

## Contribution

The study identifies behavioral and neural differences in ADHD patients during tasks involving facial affect recognition and executive function.

## Key findings

- ADHD patients showed significant differences in behavioral metrics compared to healthy controls.
- Neurophysiological differences were observed in the P3d and N170 ERP components.
- ERP measures alone may not be sufficient for screening emotional and facial processing issues in ADHD.

## Abstract

Attention-deficit/hyperactivity disorder (ADHD) affects approximately 12% of children worldwide. With a 50% chance of persistence into adulthood and associations with impairments in various domains, including social and emotional ones, early diagnosis is crucial. The exact neural substrates of ADHD are still unclear. This study aimed to reassess the behavioral and neural metrics of executive functions and neural substrates of facial affect recognition. A total of 117 ADHD patients and 183 healthy controls were evaluated by two Go/NoGo tasks: the classic visual continuous performance test and the emotional continuous performance test, which requires facial affect encoding. Group differences between ADHD subjects and healthy controls were assessed using analysis of covariance (ANCOVA), with age and sex included as covariates. Dependent variables comprised behavioral (number of omission and commission errors, reaction time, and reaction time variability) and neurophysiological measures (event-related potentials [ERPs]). As the main result, we identified significant differences between ADHD patients and healthy controls in all behavioral metrics, one neural marker of action inhibition (P3d) and the facial processing marker (N170). The differences were moderate-to-large when expressed as effect size measures in behavioral variables and small-to-moderate for neurophysiological variables. The small-to-moderate effect sizes obtained from the neurophysiological measures suggest that ERPs are insufficient as sole markers for effectively screening emotion and face processing abnormalities in ADHD.