# Editorial: The liver’s dilemma: sensing real danger in a sea of PAMPs

**Authors:** Ian N. Crispe, Andrea Henriques Pons

PMC · DOI: 10.3389/fimmu.2025.1591911 · Frontiers in Immunology · 2025-05-20

## Full-text entities

- **Genes:** Il6 (interleukin 6) [NCBI Gene 16193] {aka Il-6}, Trp53bp2 (transformation related protein 53 binding protein 2) [NCBI Gene 209456] {aka 53BP2, ASPP2, PPP1R13A, Tp53bp2}, Gzmb (granzyme B) [NCBI Gene 14939] {aka CCP-1/C11, CCP1, Ctla-1, Ctla1, GZB}, Nlrp3 (NLR family, pyrin domain containing 3) [NCBI Gene 216799] {aka AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS}, Ifng (interferon gamma) [NCBI Gene 15978] {aka IFN-g, If2f, Ifg}
- **Diseases:** tissue (MESH:D017695), viral hepatitis (MESH:D014777), cancer (MESH:D009369), Acute liver injury (MESH:D017114), infection (MESH:D007239), injury (MESH:D014947), inflammation (MESH:D007249), liver damage (MESH:D056486), liver cancer (MESH:D006528), liver injury (MESH:D017093)
- **Chemicals:** D-Galactosamine (-), K+ (MESH:D011188), glucuronic acid (MESH:D020723)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12129783