# Predictive modeling of eye lens dose in interventional radiology: a polynomial regression approach to cumulative fluoroscopy dose

**Authors:** Mengyun Wu, Fang Yuan, Yeqing Gu, Jinhan Wang, Lin Lu, Zhi Zeng

PMC · DOI: 10.3389/fpubh.2025.1547101 · Frontiers in Public Health · 2025-05-20

## TL;DR

This study creates a model to predict eye lens radiation doses for radiologists during procedures, aiming to improve safety at high exposure levels.

## Contribution

A quadratic polynomial regression model is proposed to predict eye lens dose from cumulative fluoroscopy dose in high-exposure scenarios.

## Key findings

- The quadratic model accurately predicts eye lens dose for cumulative fluoroscopy doses above 20 Gy.
- The model shows limited accuracy for doses 20 Gy, supporting radiation safety protocols in clinical practice.

## Abstract

This study aimed to investigate the relationship between cumulative fluoroscopy dose and eye lens radiation dose among interventional radiologists, and to develop a predictive model to enhance occupational radiation safety.

We collected data from interventional radiologists, focusing on cumulative fluoroscopy dose during procedures and corresponding eye lens doses. A quadratic polynomial regression model was developed to assess the non-linear relationship between cumulative fluoroscopy dose and eye lens dose. The study involved the use of machine-generated cumulative dose data and personal eye lens dosimeters.

The quadratic polynomial regression model effectively captured the non-linear relationship for cumulative doses >20 Gy, enabling precise dose prediction at higher exposure levels where cataract risks escalate. However, the model showed limited accuracy for doses ≤ 20 Gy. This model allowed for more precise prediction of eye lens dose, particularly at higher exposure levels where the risks of radiation-induced cataracts increase significantly.

The quadratic polynomial regression model serves as a potentially valuable tool for real-time monitoring in high-exposure scenarios (>20 Gy), supporting radiation safety protocols in clinical practice. Integration into routine hospital systems may enhance radiation protection protocols and inform policy development, aligning occupational dose monitoring practices with international safety standards.

## Full-text entities

- **Diseases:** cataract (MESH:D002386)

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12129769/full.md

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Source: https://tomesphere.com/paper/PMC12129769